[大鼠子宫细胞质膜中雌激素结合系统的存在]
[Presence of estrogen-binding systems in the plasma membranes of rat uterus cells].
作者信息
Sergeev P V, Denisov Iu P, Suleĭmanov S Sh
出版信息
Farmakol Toksikol. 1981 Jul-Aug;44(4):429-32.
PMID:7286201
Abstract
Steroid hormone binding by plasma membranes of rat uterine cells was studied. Estradiol and estriol were shown to be bound by a specific-saturated membrane component with a high affinity for estrogens. Netrophic corticosterone and testosterone interacted with an unsaturated membrane component. It is concluded that the saturated component is necessary for primary recognition of female hormones by uterine target cells.
摘要
对大鼠子宫细胞质膜的类固醇激素结合情况进行了研究。结果显示，雌二醇和雌三醇与一种对雌激素具有高亲和力的特异性饱和膜成分相结合。去氧皮质酮和睾酮则与一种不饱和膜成分相互作用。得出的结论是，饱和成分对于子宫靶细胞对雌性激素的初始识别是必要的。
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