Tomsick R, Menn H
Hand. 1981 Jun;13(2):177-82. doi: 10.1016/s0072-968x(81)80060-5.
Chemosurgery and wound healing by secondary intention is an excellent method of treatment for subungual carcinoma. It allows for complete ablation of the tumour with maximal preservation of tissue, eliminating the need for amputation, in the absence of bone involvement. As most nail bed carcinomas occur on the thumb, by avoiding distal phalanx amputation one can prevent considerable disability. Because chemosurgery traces out every infiltrating band of tumour, bone involvement can be accurately detected. Amputation, if necessary, could then be carried out to achieve cure. Despite the age of our patients (averaged age 64.6 years), all surgical sites healed well with good range of motion at the adjacent interphalangeal joint.
化学外科手术及二期愈合伤口是治疗甲下癌的一种极佳方法。在无骨质受累的情况下,它能在最大程度保留组织的同时完全切除肿瘤,从而无需进行截肢手术。由于大多数甲床癌发生在拇指,通过避免远端指骨截肢可预防相当程度的功能障碍。因为化学外科手术能追踪肿瘤的每一条浸润带,所以可准确检测到骨质受累情况。如有必要,随后可进行截肢以实现治愈。尽管我们的患者年龄较大(平均年龄64.6岁),但所有手术部位均愈合良好,相邻指间关节活动范围正常。