LaVail M M
J Hered. 1981 Jul-Aug;72(4):294-6. doi: 10.1093/oxfordjournals.jhered.a109506.
The retinal dystrophy gene, rdy, in the rat displays autosomal linkage of 19.0 +/- 1.7 percent with nonagouti, a, and 31.8 +/- 4.1 percent with Svp-1 in linkage group IV. The data are consistent with the linear order rdy--a--Svp-1, but the orientation of this sequence with respect to the centromere is not known. A congenic strain has been developed from some of the testcross animals in which retinal dystrophic and heterozygous control rats of both pink-eyed and black-eyed phenotyped can be distinguished with pigmentation marker genes.
大鼠中的视网膜营养不良基因rdy在第四连锁群中与非鼠灰色基因a呈19.0±1.7%的常染色体连锁,与Svp-1呈31.8±4.1%的常染色体连锁。数据与线性顺序rdy—a—Svp-1一致,但该序列相对于着丝粒的方向尚不清楚。已经从一些测交动物中培育出了一个同类系,在这个同类系中,患有视网膜营养不良的大鼠以及具有粉红眼和黑眼表型的杂合对照大鼠可以通过色素沉着标记基因加以区分。