Runge W, Younger B, Zelickson A S
J Invest Dermatol. 1981 Nov;77(5):421-9. doi: 10.1111/1523-1747.ep12495258.
The internal structure of the epidermal Langerhans' cell granule (LCG) was studied with optical transforms of electron micrographs representing 3 planes of sectioning. Its "limiting membrane" exhibited linear discontinuity with a periodicity of about 11 nm similar to the structural repeats of the core (10.8 mm) in both the "outer" and the "internal leaflets". The average thickness of the nonvesicular part of the LCG was 55.7 nm. Disarray present in the optical diffractograms was incompatible with crystallinic or paracrystallinic orderliness of the periodic structures in the LCG. The structure appeared as an assembly of 4 sheets of roughly hexagonally packed particles: The stacked particles of 2 sheets in orthogonal contact forming the core (13.2 nm) were separated by an intermediate space (2.7 nm) from the single sheet of the outer layer and staggered by one-half the particle diameter on cross-sections. The validity of this model was inferred from the similarity of optical transforms of model structures.
利用代表三个切片平面的电子显微照片的光学变换，研究了表皮朗格汉斯细胞颗粒（LCG）的内部结构。其“限制膜”呈现出线性间断，周期约为11纳米，类似于“外层”和“内层小叶”中核心（10.8纳米）的结构重复。LCG非囊泡部分的平均厚度为55.7纳米。光学衍射图中呈现的无序与LCG中周期性结构的晶体或准晶体有序性不相符。该结构看起来像是由4层大致呈六边形堆积的颗粒组成的集合体：正交接触形成核心（13.2纳米）的2层堆叠颗粒，与外层的单层颗粒由一个中间空间（2.7纳米）隔开，并且在横截面上错开颗粒直径的一半。该模型的有效性是从模型结构光学变换的相似性推断出来的。
