Drouet L, Legrand Y, Fauvel F, Birembaut P
J Mal Vasc. 1981;6(1):13-5.
In view of its anatomical position, physical characteristics and metabolism, the endothelial cell plays a major part in maintaining the integrity of the vascular system and in the relation between the blood content, both plasma and blood cells, and the wall structure. Where this continuous single layer undergoes anatomical or functional changes, a new equilibrium is set up, an equilibrium which is multifactorial and dynamic. It is governed by the vascular and blood components and by their interrelation; it varies as a function of time and of the biorheological conditions. The interrelationship between the blood content and the wall plays an important part in vascular pathology, especially of the degenerative and thrombotic type. A better understanding of these factors will enhance the possibility of preventing atherogenesis and lay the basis for a coherent and effective therapeutic attitude thrombosis.
鉴于其解剖位置、物理特性和代谢情况，内皮细胞在维持血管系统的完整性以及血浆和血细胞等血液成分与血管壁结构之间的关系方面发挥着重要作用。当这一连续的单层细胞发生解剖学或功能变化时，会建立起一种新的平衡，这种平衡是多因素且动态的。它受血管和血液成分及其相互关系的支配；会随着时间和生物流变学条件而变化。血液成分与血管壁之间的相互关系在血管病理学中，尤其是在退行性和血栓形成类型的血管病理学中起着重要作用。更好地理解这些因素将增加预防动脉粥样硬化的可能性，并为形成连贯有效的血栓治疗态度奠定基础。
