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慢性耐药性癫痫患者接受切除性手术的选择:5年经验

Selection of patients with chronic drug-resistant epilepsy for resective surgery: 5 years' experience.

作者信息

Polkey C E

出版信息

J R Soc Med. 1981 Aug;74(8):574-9. doi: 10.1177/014107688107400804.

DOI:10.1177/014107688107400804
PMID:7288792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1438896/
Abstract

Selection criteria are the key to success in resective surgery for intractable epilepsy. Using such criteria about 50% of patients admitted for assessment are considered unsuitable, half of these for neurophysiological reasons or because there is evidence of more than one area of structural abnormality. Selection for a good result from temporal lobectomy can be judged, both on the proportion of positive pathological lesions in the resected temporal lobes and on a high degree of seizure relief together with a low incidence of side effects. The same holds for other resections. The relationship between these factors is reviewed.

摘要

选择标准是难治性癫痫切除性手术成功的关键。根据这些标准,约50%入院评估的患者被认为不适合手术,其中一半是由于神经生理学原因或存在不止一个结构异常区域的证据。颞叶切除术能否取得良好效果,可以根据切除的颞叶中阳性病理病变的比例、癫痫发作缓解程度高以及副作用发生率低来判断。其他切除术也是如此。本文综述了这些因素之间的关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3991/1438896/6995f67c9965/jrsocmed00258-0020-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3991/1438896/2dea2c369468/jrsocmed00258-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3991/1438896/6995f67c9965/jrsocmed00258-0020-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3991/1438896/2dea2c369468/jrsocmed00258-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3991/1438896/6995f67c9965/jrsocmed00258-0020-b.jpg

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1
Selection of patients with chronic drug-resistant epilepsy for resective surgery: 5 years' experience.慢性耐药性癫痫患者接受切除性手术的选择:5年经验
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引用本文的文献

1
Effects of anterior temporal lobectomy apart from the relief of seizures: a study of 40 patients.颞叶前部切除术除缓解癫痫发作外的效果:40例患者的研究
J R Soc Med. 1983 May;76(5):354-8. doi: 10.1177/014107688307600505.

本文引用的文献

1
Infantile hemiplegia treated by removing one cerebral hemisphere.通过切除一个大脑半球治疗小儿偏瘫。
J Neurol Neurosurg Psychiatry. 1950 Nov;13(4):243-67. doi: 10.1136/jnnp.13.4.243.
2
Selection of patients with intractable epilepsy for resective surgery.
Arch Dis Child. 1980 Nov;55(11):841-4. doi: 10.1136/adc.55.11.841.
3
Surgery for epilepsy.癫痫手术
Br J Hosp Med. 1981 Jan;25(1):48-57.
4
Genetic and related aetiological factors in temporal lobe epilepsy. A review.
Epilepsia. 1971 Mar;12(1):13-31. doi: 10.1111/j.1528-1157.1971.tb03912.x.
5
Reversibility by temporal-lobe resection of the behavioral abnormalities of temporal-lobe epilepsy.
N Engl J Med. 1973 Aug 30;289(9):451-5. doi: 10.1056/NEJM197308302890904.