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论生物系统的起源及多核苷酸的作用——进化的起始、遗传密码的结构基础与蛋白质生物合成机制

On the origin of biological systems and the role of poly-nucleotides -- the initiation of evolution, the structural basis of the genetic code and the mechanism of protein biosynthesis.

作者信息

Thomas B R

出版信息

Med Hypotheses. 1981 Apr;7(4):455-66. doi: 10.1016/0306-9877(81)90032-3.

Abstract

There is much information on the nature and function of biological systems in the structures of the small molecules that affect them and in the biosynthetic and other reactions in which they are involved. Combining this with biochemical and polynucleotide sequence information allows us to derive explanations for a number of biological problems that earlier were unclear or even quite obscure. Thus polynucleotide systems give a good account of the origin of life, of the genetic code and of the function of the ribosomal mechanism of protein biosynthesis. It is apparent that polynucleotides play a more important role than has been fully appreciated.

摘要

在影响生物系统的小分子结构中,以及在它们所参与的生物合成和其他反应中,存在着大量关于生物系统的性质和功能的信息。将这些信息与生化和多核苷酸序列信息相结合,使我们能够对一些以前不清楚甚至相当模糊的生物学问题作出解释。因此,多核苷酸系统很好地解释了生命的起源、遗传密码以及蛋白质生物合成的核糖体机制的功能。显然,多核苷酸所起的作用比人们充分认识到的更为重要。

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