Katzeff I E, Gathiram P, Edwards H, Booyens J
Med Hypotheses. 1981 Jul;7(7):863-84. doi: 10.1016/0306-9877(81)90042-6.
This paper experimentally evaluates the "imaginary cardiac vector" hypothesis, that the cardiac vector is not a real vector. We have previously shown on theoretical grounds that the basis of the cardiac vector is invalid in that Einthoven used scalar, not vector, procedures. Attempts by subsequent workers to compensate for the theoretical flaws have not succeeded. The concept of the "cardiac vector" which they have invented has the dimensions of an imaginary entity. Experimental measurement of isopotential maps derived from dipoles in a volume conductor demonstrates that these dipoles do not summate vectorially. Isopotential maps of the thoracic surface confirm that this applies to the human ECG. An imaginary "man-frog" cardiac vector loop is demonstrated using a lead from a man and a lead from a frog. This illustrates that the "imaginary cardiac vector" is a tenable concept. Finally, a crucial test of the hypothesis is reported which demonstrates that exercise causes deviations of the so-called cardiac vector in opposite directions, simultaneously, in different VCG lead systems. Since a physical entity can only be in one place and more in one direction at a particular instant, this experiment invalidates the "real cardiac vector" hypothesis. This strongly suggests that the cardiac vector is a brilliant, but imaginary, construction with immense clinical value, especially in the interpretation of the sequence of depolarization. Nevertheless, it obstructs analysis of the real basis of the electricity of the heart.
本文通过实验评估了“假想心脏向量”假说,即心脏向量并非真实向量。我们之前基于理论依据表明,心脏向量的基础是无效的,因为艾因托芬使用的是标量而非向量方法。后续研究人员试图弥补这些理论缺陷,但均未成功。他们所发明的“心脏向量”概念具有虚数实体的量纲。对体积导体中偶极子产生的等电位图进行实验测量表明,这些偶极子并非向量叠加。胸壁表面的等电位图证实这也适用于人体心电图。通过使用来自人体的导联和来自青蛙的导联展示了一个假想的“人 - 蛙”心脏向量环。这表明“假想心脏向量”是一个合理的概念。最后,报告了对该假说的一项关键测试,该测试表明运动在不同的心向量图导联系统中同时导致所谓的心脏向量向相反方向偏移。由于一个物理实体在特定时刻只能处于一个位置且朝一个方向,该实验使“真实心脏向量”假说无效。这有力地表明,心脏向量是一个虽精妙但假想的构建,具有巨大的临床价值,尤其是在解释去极化序列方面。然而,它阻碍了对心脏电活动真实基础的分析。