对豚鼠中由5-羟色氨酸诱导的肌阵挛进行的药理学分析表明，大脑中存在多种5-羟色胺受体。 - Suppr

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Pharmacological analysis of the myoclonus induced by 5-hydroxytryptophan in the guinea pig suggests the presence of multiple 5-hydroxytryptamine receptors in the brain.

作者信息

Luscombe G, Jenner P, Marsden C D

出版信息

Neuropharmacology. 1981 Sep;20(9):819-31. doi: 10.1016/0028-3908(81)90074-5.

DOI:10.1016/0028-3908(81)90074-5

PMID:7290355

Abstract

摘要

相似文献

Pharmacological analysis of the myoclonus induced by 5-hydroxytryptophan in the guinea pig suggests the presence of multiple 5-hydroxytryptamine receptors in the brain.对豚鼠中由5-羟色氨酸诱导的肌阵挛进行的药理学分析表明，大脑中存在多种5-羟色胺受体。

Neuropharmacology. 1981 Sep;20(9):819-31. doi: 10.1016/0028-3908(81)90074-5.

Correlation of [3H]5-hydroxytryptamine (5HT) binding to brain stem preparations and the production and prevention of myoclonus in guinea pig by 5HT agonists and antagonists.

Eur J Pharmacol. 1984 Sep 17;104(3-4):235-44. doi: 10.1016/0014-2999(84)90398-4.

5-Hydroxytryptophan-induced myoclonus in guinea pigs: mediation through 5-HT1/2 receptor subtypes.5-羟色氨酸诱导豚鼠肌阵挛：通过5-羟色胺1/2受体亚型介导

Eur J Pharmacol. 1998 Apr 17;347(1):51-6. doi: 10.1016/s0014-2999(98)00086-7.

Myoclonus in guniea pigs is induced by indole-containing but not piperazine-containing 5HT agonists.豚鼠的肌阵挛是由含吲哚而非含哌嗪的5-羟色胺激动剂诱发的。

Life Sci. 1982 Apr 26;30(17):1487-94. doi: 10.1016/0024-3205(82)90563-x.

Head and whole-body jerking in guinea pigs are differentially modulated by 5-HT1A, 5-HT1B/1D and 5-HT2A receptor antagonists.5-HT1A、5-HT1B/1D和5-HT2A受体拮抗剂对豚鼠的头部和全身抽搐有不同的调节作用。

Eur J Pharmacol. 1998 Nov 20;361(2-3):185-90. doi: 10.1016/s0014-2999(98)00746-8.

L-5-Hydroxytryptophan-induced myoclonus in guinea pigs: a model for the study of central serotonin-dopamine interactions.L-5-羟色氨酸诱导的豚鼠肌阵挛：一种用于研究中枢5-羟色胺-多巴胺相互作用的模型。

Neuropharmacology. 1978 Nov;17(11):947-55. doi: 10.1016/0028-3908(78)90137-5.

Brainstem serotonin receptors in the guinea pig: implications for myoclonus.豚鼠脑干5-羟色胺受体：对肌阵挛的影响

Neuropharmacology. 1993 Mar;32(3):209-15. doi: 10.1016/0028-3908(93)90102-9.

Levodopa-induced myoclonus.

Arch Neurol. 1975 May;32(5):330-4. doi: 10.1001/archneur.1975.00490470075011.

5-Hydroxytryptamine (5-HT)-dependent myoclonus in guinea pigs is induced through brainstem 5-HT-1 receptors.

Neurosci Lett. 1984 Feb 24;44(3):241-6. doi: 10.1016/0304-3940(84)90029-6.

5-HT-mediated myoclonus in the guinea pig as a model of brainstem 5-HT and tryptamine receptor action.以豚鼠5-羟色胺介导的肌阵挛作为脑干5-羟色胺和色胺受体作用的模型。

Adv Neurol. 1986;43:529-43.

引用本文的文献

Effects of 8-OHDPAT and 5-HT1A antagonists WAY100135 and WAY100635, on guinea-pig behaviour and dorsal raphe 5-HT neurone firing.8-羟基二苯丙氨酸（8-OHDPAT）以及5-羟色胺1A（5-HT1A）拮抗剂WAY100135和WAY100635对豚鼠行为及中缝背核5-羟色胺能神经元放电的影响。

Br J Pharmacol. 1996 Feb;117(4):750-6. doi: 10.1111/j.1476-5381.1996.tb15254.x.

Studies on the role of serotonin in different regions of the rat central nervous system on pentylenetetrazol-induced seizures and the effect of di-n-propylacetate.关于5-羟色胺在大鼠中枢神经系统不同区域对戊四氮诱发癫痫发作的作用及二正丙基乙酸酯影响的研究

Naunyn Schmiedebergs Arch Pharmacol. 1983 Mar;322(2):147-52. doi: 10.1007/BF00512388.

Differential behavioral effects of tryptophan and 5-hydroxytryptophan in vervet monkeys: influence of catecholaminergic systems.色氨酸和5-羟色氨酸对黑长尾猴行为的不同影响：儿茶酚胺能系统的作用

Psychopharmacology (Berl). 1987;93(1):44-50. doi: 10.1007/BF02439585.

The pharmacological characterisation of pilocarpine-induced purposeless chewing behaviour in the rat.毛果芸香碱诱导大鼠无目的咀嚼行为的药理学特征

Psychopharmacology (Berl). 1988;96(1):55-62. doi: 10.1007/BF02431533.

Pharmacological characterisation of spontaneous or drug-associated purposeless chewing movements in rats.大鼠自发性或药物相关无目的咀嚼运动的药理学特征

Psychopharmacology (Berl). 1985;85(1):71-9. doi: 10.1007/BF00427326.

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