Barrère M, Géraud G, Auvergnat J C, Bes A
Nouv Presse Med. 1981 Oct 3;10(35):2889-91.
In a 32-year-old woman with mitral prolapse, bacterial endocarditis was preceded by a long period of neuralgias and skin lesions. Thrombosis of the Sylvian artery heralded the onset of the disease which remained for a long time apyretic and was marked by several cerebral vascular accidents. After failure of antibiotic therapy the mitral valve was replaced by a Starr valve and the patient recovered. In view of the presence of immunological abnormalities in this patient, the mechanisms of the vascular lesions is discussed. Many authors are new giving a large place to "immunoallergic" theories in their attempts to explain the occurrence of non-specific arteritis in bacterial endocarditis.
一名32岁患有二尖瓣脱垂的女性,在发生细菌性心内膜炎之前有很长一段时间的神经痛和皮肤病变。大脑中动脉血栓形成预示着疾病的发作,该疾病在很长一段时间内无发热症状,并以几次脑血管意外为特征。抗生素治疗失败后,二尖瓣被Starr瓣膜置换,患者康复。鉴于该患者存在免疫异常,本文讨论了血管病变的机制。许多作者在试图解释细菌性心内膜炎中非特异性动脉炎的发生时,越来越重视“免疫过敏”理论。