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[胃癌。408例接受手术治疗患者的可切除性及生存率(作者译)]

[Carcinoma of the stomach. Resectability and survival rates in 408 operated patients (author's transl)].

作者信息

Moreaux J, Montupet P

出版信息

Nouv Presse Med. 1981 Oct 24;10(38):3133-6.

PMID:7290975
Abstract

In 125 cases (30,6%) the tumour could not be removed, mainly because of peritoneal metastases and posterior extra-gastric extension. Tumoral resection was performed in 283 cases (69.4%), being palliative in 76 and considered as curative in 216 (52.9%). There were 177 distal gastrectomies, 40 proximal and 66 total gastrectomies with oesophageal resection adapted to the extent of the tumour. Operative mortality was 2.1% after resection and 8% after exploratory and derivative surgery. The five-year survival rates among 213 patients operated upon before December 1973, were 50.8% after curative resection, 39% for all resections and 27.7% for all patients who underwent surgery. The long-term prognosis was evaluated in relation to the site of the lesion, its depth of penetration into the gastric wall and its extension to the lymph nodes. Spreading superficial carcinomas had a five-year survival rate of 89.6% and their incidence (14% of all operated patients) did not change in recent years despite the increasing use of gastric endoscopy. Extension to the lymph nodes was a very important prognostic factor, since the five-year survival rate was 75% in patients with non-invaded primary lymph nodes, as opposed to 32% in patients with invaded primary lymph nodes and only 5% in patients with secondary node involvement.

摘要

125例(30.6%)肿瘤无法切除,主要原因是腹膜转移和胃外后侧浸润。283例(69.4%)进行了肿瘤切除,其中76例为姑息性切除,216例(52.9%)为根治性切除。有177例远端胃切除术、40例近端胃切除术和66例全胃切除术并根据肿瘤范围进行了食管切除。切除术后手术死亡率为2.1%,探查及衍生手术后为8%。1973年12月前接受手术的213例患者中,根治性切除后五年生存率为50.8%,所有切除术后为39%,接受手术的所有患者为27.7%。根据病变部位、胃壁浸润深度及其向淋巴结的扩展情况评估长期预后。浅表扩散性癌的五年生存率为89.6%,尽管近年来胃镜检查的使用增加,但其发病率(占所有手术患者的14%)并未改变。向淋巴结的扩展是一个非常重要的预后因素,因为未侵犯初级淋巴结的患者五年生存率为75%,而侵犯初级淋巴结的患者为32%,继发淋巴结受累的患者仅为5%。

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