• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Selective stimulation of intracardiac pre-ganglionic vagal fibres of the dog atrium.

作者信息

Chiba S

出版信息

Clin Exp Pharmacol Physiol. 1978 Sep-Oct;5(5):465-9. doi: 10.1111/j.1440-1681.1978.tb00698.x.

DOI:10.1111/j.1440-1681.1978.tb00698.x
PMID:729205
Abstract
  1. Direct electrical stimulation (0.05 ms, 5.0 V and 30 Hz) caused negative chronotropic and inotropic effects on the blood-perfused, isolated dog atrium. 2. These negative effects of electrical stimulation were significantly blocked not only by treatment with atropine or tetrodotoxin, but also by hexamethonium, although hexamethonium did not modify the effects of injected acetylcholine. 3. These results suggest that direct electrical stimulation on the isolated, blood-perfused dog atrium readily causes a release of acetylcholine by excitation of parasympathetic pre-ganglionic fibers.
摘要

相似文献

1
Selective stimulation of intracardiac pre-ganglionic vagal fibres of the dog atrium.
Clin Exp Pharmacol Physiol. 1978 Sep-Oct;5(5):465-9. doi: 10.1111/j.1440-1681.1978.tb00698.x.
2
A pharmacologic analysis of chronotropic and inotropic responses to direct electrical stimulation of the isolated, blood-perfused canine atrium.对离体、血液灌注犬心房进行直接电刺激时变时性和变力性反应的药理学分析。
Jpn Heart J. 1980 Nov;21(6):873-82. doi: 10.1536/ihj.21.873.
3
Blocking effects of alinidine on negative chronotropic and inotropic responses to vagal stimulation and injected acetylcholine and carbachol in dogs.
J Pharmacol Exp Ther. 1987 Dec;243(3):1113-20.
4
Muscarinic suppression of the nicotinic action of acetylcholine on the isolated, blood-perfused atrium of the dog.毒蕈碱对乙酰胆碱在犬离体血液灌注心房上烟碱样作用的抑制。
Naunyn Schmiedebergs Arch Pharmacol. 1975;289(3):315-25. doi: 10.1007/BF00499984.
5
The mode of action of 4-aminopyridine on the chronotropic and inotropic responses in the isolated, blood-perfused dog heart.4-氨基吡啶对离体血液灌注犬心脏变时性和变力性反应的作用方式。
Eur J Pharmacol. 1985 Aug 27;114(3):317-23. doi: 10.1016/0014-2999(85)90376-0.
6
Differential intracardiac sympathetic and parasympathetic innervation to the SA and AV nodes in anesthetized dog hearts.麻醉犬心脏中窦房结和房室结的心脏内交感神经和副交感神经的差异性支配。
Jpn J Pharmacol. 1991 Mar;55(3):381-90. doi: 10.1254/jjp.55.381.
7
The actions of myelinated and non-myelinated vagal fibres on atrial contraction in the rabbit.有髓鞘和无髓鞘迷走神经纤维对家兔心房收缩的作用。
J Auton Nerv Syst. 1988 Feb;22(1):67-73. doi: 10.1016/0165-1838(88)90155-5.
8
Selective stimulation of the parasympathetic preganglionic nerve fibres in the excised and blood-perfused SA node preparation of the dog.在犬的离体且有血液灌注的窦房结标本中，对副交感神经节前神经纤维进行选择性刺激。
Naunyn Schmiedebergs Arch Pharmacol. 1973;278(2):135-50. doi: 10.1007/BF00500646.
9
Potentiating effects of 4-aminopyridine on responses to intramural vagal stimulation in the isolated dog atrium.
Eur J Pharmacol. 1985 May 28;112(1):89-95. doi: 10.1016/0014-2999(85)90242-0.
10
Fade responses at neuroeffector junction to vagal stimulation in the isolated, blood-perfused dog atrium.在离体、血液灌注的犬心房中，迷走神经刺激引起的神经效应器接头处反应的消退。
Jpn J Physiol. 1988;38(3):345-59. doi: 10.2170/jjphysiol.38.345.

引用本文的文献

1
Extracellular ATP and β-NAD alter electrical properties and cholinergic effects in the rat heart in age-specific manner.细胞外 ATP 和 β-NAD 以年龄特异性方式改变大鼠心脏的电特性和胆碱能效应。
Purinergic Signal. 2019 Mar;15(1):107-117. doi: 10.1007/s11302-019-09645-6. Epub 2019 Feb 12.