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[根治性手术后胃癌患者红细胞的己糖激酶和乳酸脱氢酶活性、乳酸和丙酮酸含量及酸碱平衡]

[Hexokinase and lactate dehydrogenase activity, lactic and pyruvic acid content of erythrocytes and acid-base equilibrium in stomach cancer patients after radical operations].

作者信息

Golub I Kh, Kazantsev F N

出版信息

Vopr Onkol. 1981;27(9):24-7.

PMID:7293089
Abstract

Certain glycolytic enzymes, the level of end metabolites of glycolysis and acid-base equilibrium indices were studied in 106 patients with stomach tumors (stage II-III). It was found that prior to surgery metabolic disturbances in erythrocytes are to be observed, while acid-base indices tend toward metabolic acidosis. After radical surgery, the activity levels of hexokinase and lactate, dehydrogenase as well as concentrations of lactic and pyruvic acids are decreased, acid-base equilibrium being restored much earlier.

摘要

对106例II - III期胃肿瘤患者的某些糖酵解酶、糖酵解终代谢产物水平及酸碱平衡指标进行了研究。结果发现,术前可观察到红细胞中的代谢紊乱,而酸碱指标倾向于代谢性酸中毒。根治性手术后,己糖激酶和乳酸脱氢酶的活性水平以及乳酸和丙酮酸的浓度降低,酸碱平衡恢复得更早。

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