Mauersberger S, Schunck W H, Müller H H
Z Allg Mikrobiol. 1981;21(4):313-21. doi: 10.1002/jobm.3630210407.
In the alkane-utilizing yeast strain Lodderomyces elongisporus cytochrome P-450 is induced by aliphatic hydrocarbons and to a lesser degree also by some of their derivatives. Cycloheximide and glucose inhibit the induction process, the former by inhibition of cytoplasmic translation, the latter presumably by catabolite repression. Among the nearly 40 checked compounds tetradecane and 1-tetradecene are the most effective inducers. The branching of the alkyl chain as well as the terminal introduction of electrophilic atoms decrease the induction effect.
在利用烷烃的酵母菌株长孢洛德酵母中，细胞色素P - 450由脂肪烃诱导，某些脂肪烃衍生物也能在较小程度上诱导其产生。环己酰亚胺和葡萄糖会抑制诱导过程，前者通过抑制细胞质翻译起作用，后者可能是通过分解代谢物阻遏发挥作用。在近40种检测的化合物中，十四烷和1 - 十四碳烯是最有效的诱导剂。烷基链的分支以及亲电原子的末端引入会降低诱导效果。
