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[癫痫患者的骨髓造血功能]

[Bone marrow hematopoiesis in epileptics].

作者信息

Shapiro Iu L, Vaĭntrub M Ia, Levina L F

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1981;81(6):842-5.

PMID:7293582
Abstract

In 72 epileptic patients the bone marrow was examined in various periods of epileptic paroxysms. It was found that the morphological composition of the medullary hemopoiesis was characterized by a myeloid reaction and a lowered mitotic activity of the bone marrow elements. All the shifts in the functional state of the medullary hemopoiesis correlated with the paroxysm periods and were reflected adequately in the peripheral blood picture. The states described differed sharply from the anomalous medullary hemopoiesis observed in epileptic patients having hematological complications, e.g. pernicious anemia caused by phenobarbital, hexamidine and diphenin.

摘要

对72例癫痫患者在癫痫发作的不同阶段进行了骨髓检查。发现骨髓造血的形态学组成具有髓样反应特征,且骨髓细胞的有丝分裂活性降低。骨髓造血功能状态的所有变化均与发作期相关,并在外周血图片中得到充分反映。所描述的这些状态与患有血液学并发症(如苯巴比妥、己脒定和双苯丙胺引起的恶性贫血)的癫痫患者中观察到的异常骨髓造血明显不同。

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