Sudeck M, Hosenfeld D, Grote W
Dtsch Med Wochenschr. 1978 Dec 29;103(52):2076-8. doi: 10.1055/s-0028-1129400.
The detection rate for female carriers of haemophilia A was investigated by comparing the one-step method of Hardisty and Macpherson for biological activity of factor VIII with quantitative immunoelectrophoresis (after Laurell) for factor VIII-associated antigen. Certain or probable positive results were obtained in 25 of 27 female carriers by the quantitative immunoelectrophoresis, but only in 18 when measuring factor VIII activity.
通过将用于检测因子VIII生物活性的哈迪斯蒂和麦克弗森一步法与用于检测因子VIII相关抗原的(劳雷尔之后的)定量免疫电泳法进行比较,研究了甲型血友病女性携带者的检出率。通过定量免疫电泳法,在27名女性携带者中有25名获得了确定或可能的阳性结果,但在检测因子VIII活性时,只有18名获得阳性结果。