Zerbino D D
Arkh Patol. 1981;43(8):42-7.
Vasculitis was detected in 5 patients although not in the temporal artery but in vessels of other localizations: subcutaneous veins of the lower extremities (an adolescent of 17 and a man of 41), cardiac and renal arteries (a man of 32), gall bladder artery (a woman of 72), veins of the spermatic cord (a man of 28). Giant cells formed in granulomatous reaction, most frequently in the intima of the vessel or close to it in such nosological forms as endarteritis, periarteritis nodosa, obliterating thromboangiitis (Buerger's disease). A hypothesis is suggested concerning the etiological role in the development of giant cell vasculitis of chemical haptens (xenobiotics), protozoa, possibly bacteria and viruses.
5例患者检测到血管炎,不过并非在颞动脉,而是在其他部位的血管:下肢皮下静脉(1名17岁青少年和1名41岁男性)、心脏和肾动脉(1名32岁男性)、胆囊动脉(1名72岁女性)、精索静脉(1名28岁男性)。在肉芽肿反应中形成巨细胞,最常见于血管内膜或在诸如动脉内膜炎、结节性多动脉炎、闭塞性血栓性血管炎(伯格病)等疾病形式中靠近血管内膜处。有人提出一种假说,认为化学半抗原(外源性生物活性物质)、原生动物,可能还有细菌和病毒在巨细胞血管炎的发生中具有病因学作用。