Gallant C A, Clement J G
Can J Physiol Pharmacol. 1981 Aug;59(8):886-9. doi: 10.1139/y81-133.
In the electrically stimulated guinea pig ileum longitudinal muscle strip preparation the inhibitory actions of adenosine were antagonized by various concentrations of theophylline (12.5 and 100 micro M) and 8-phenyltheophylline (4 and 20 micro M). However, the inhibitory actions of morphine were not antagonized by the same concentration of theophylline and 8-phenyltheophylline. These results suggest that in the guinea pig ileum longitudinal muscle-strip adenosine is not a mediator in the inhibitory actions of morphine.
在电刺激豚鼠回肠纵肌条标本中，不同浓度的茶碱（12.5和100微摩尔）和8-苯基茶碱（4和20微摩尔）可拮抗腺苷的抑制作用。然而，相同浓度的茶碱和8-苯基茶碱不能拮抗吗啡的抑制作用。这些结果表明，在豚鼠回肠纵肌条中，腺苷不是吗啡抑制作用的介质。
