Richmond J M, Whitworth J A, Kincaid-Smith P S
Clin Nephrol. 1981 Sep;16(3):109-13.
Hereditary nephritis is a well recognized disease, but its clinical manifestations and patterns of inheritance are variable. We report a family with hereditary renal disease in which the morphological lesion is interstitial nephritis and the pattern of inheritance autosomal dominant. In contrast with previous reports, microscopic/macroscopic hematuria was not a consistent marker for renal involvement. The family also demonstrates the inheritance of rheumatoid arthritis in an autosomal dominant pattern, not temporally related to the interstitial renal disease.
遗传性肾炎是一种广为人知的疾病，但其临床表现和遗传模式各不相同。我们报告了一个患有遗传性肾病的家族，其中形态学病变为间质性肾炎，遗传模式为常染色体显性遗传。与先前的报告不同，镜下/肉眼血尿并非肾脏受累的一致标志。该家族还显示类风湿关节炎以常染色体显性模式遗传，与间质性肾病在时间上无关。
