Scowcroft C W, Sanowski R A, Kozarek R A
Gastrointest Endosc. 1981 Aug;27(3):156-61. doi: 10.1016/s0016-5107(81)73182-1.
Fifteen patients with ischemia of the colon are presented. The majority showed a similar clinical presentation with hematochezia, abdominal pain, and diarrhea in an elderly patient population having associated disease. Colonoscopy was abnormal in all patients studied. Three endoscopic stages were recognized; (1) acute stage characterized by petechiae, pallor, and hyperemia; (2) subacute stage consisting of ulceration and exudation; and (3) chronic stage characterized by stricture, decrease in haustrations, and mucosal granularity. Conventional barium enemas were abnormal and suggested ischemic colitis in six of 15 patients. Rigid proctoscopy was normal or demonstrated nonspecific proctitis in 12 of 15 patients studied. Colonoscopic biopsies demonstrated superficial inflammatory changes in all patients. Thirteen patients had complete mucosal healing endoscopically in 2 weeks to 3 months with stricture developing in four patients. Because ischemic colitis is a distinct subtype of ischemic bowel disease most often limited to the superficial mucosa, colonoscopy is an alternative and usually safe modality in the diagnosis of this entity and proved more accurate that conventional x-ray and proctoscopy.
本文报告了15例结肠缺血患者。大多数患者临床表现相似,在患有相关疾病的老年人群中出现便血、腹痛和腹泻。所有接受研究的患者结肠镜检查均异常。内镜检查可分为三个阶段:(1)急性期,特征为瘀点、苍白和充血;(2)亚急性期,包括溃疡和渗出;(3)慢性期,特征为狭窄、结肠袋减少和黏膜颗粒状改变。15例患者中6例常规钡灌肠异常,提示缺血性结肠炎。15例接受研究的患者中12例硬式直肠镜检查正常或显示非特异性直肠炎。结肠镜活检显示所有患者均有浅表性炎症改变。13例患者在2周内至3个月内镜下黏膜完全愈合,4例患者出现狭窄。由于缺血性结肠炎是缺血性肠病的一种独特亚型,通常局限于浅表黏膜,结肠镜检查是诊断该病的一种替代方法,通常较为安全,且被证明比传统的X线检查和直肠镜检查更准确。