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Response of human neutrophils to C5a: a role for the oligosaccharide moiety of human C5ades Arg-74 but not of C5a in biologic activity.

作者信息

Gerard C, Chenoweth D E, Hugli T E

出版信息

J Immunol. 1981 Nov;127(5):1978-82.

PMID:7299121
Abstract
摘要

相似文献

1
Response of human neutrophils to C5a: a role for the oligosaccharide moiety of human C5ades Arg-74 but not of C5a in biologic activity.人中性粒细胞对C5a的反应：人C5a去精氨酸-74的寡糖部分而非C5a在生物活性中起作用。
J Immunol. 1981 Nov;127(5):1978-82.
2
Chemotactic response to human C3a and C5a anaphylatoxins. I. Evaluation of C3a and C5a leukotaxis in vitro and under stimulated in vivo conditions.对人C3a和C5a过敏毒素的趋化反应。I. C3a和C5a在体外及体内刺激条件下白细胞趋化性的评估。
J Immunol. 1978 Jan;120(1):109-15.
3
Human C5a des Arg increases vascular permeability.人C5a去精氨酸产物可增加血管通透性。
J Immunol. 1981 Dec;127(6):2376-80.
4
Anaphylatoxin-induced neutrophil chemotaxis and aggregation. Limited aggregation and specific desensitization induced by human C3a and synthetic C3a octapeptides.过敏毒素诱导的中性粒细胞趋化性和聚集。人C3a和合成C3a八肽诱导的有限聚集和特异性脱敏。
Int Arch Allergy Appl Immunol. 1987;82(1):4-9. doi: 10.1159/000234281.
5
Induction of lysosomal enzyme secretion by alveolar macrophages in response to the purified complement fragments C5a and C5a des-arg.肺泡巨噬细胞对纯化的补体片段C5a和C5a去精氨酸的反应诱导溶酶体酶分泌。
J Immunol. 1979 Dec;123(6):2511-7.
6
Attachment of human C5a des Arg to its cochemotaxin is required for maximum expression of chemotactic activity.人C5a去精氨酸产物与共趋化因子结合对于趋化活性的最大表达是必需的。
J Clin Invest. 1986 Dec;78(6):1589-95. doi: 10.1172/JCI112751.
7
Demonstration of specific C5a receptor on intact human polymorphonuclear leukocytes.完整人多形核白细胞上特异性C5a受体的证实。
Proc Natl Acad Sci U S A. 1978 Aug;75(8):3943-7. doi: 10.1073/pnas.75.8.3943.
8
Identification of classical anaphylatoxin as the des-Arg form of the C5a molecule: evidence of a modulator role for the oligosaccharide unit in human des-Arg74-C5a.经典过敏毒素鉴定为C5a分子的去精氨酸形式：人去精氨酸74-C5a中寡糖单元调节作用的证据。
Proc Natl Acad Sci U S A. 1981 Mar;78(3):1833-7. doi: 10.1073/pnas.78.3.1833.
9
Biologically active complement (C5)-derived peptides and their relevance to disease.具有生物活性的补体（C5）衍生肽及其与疾病的相关性。
Crit Rev Oncol Hematol. 1984;1(3):199-225. doi: 10.1016/s1040-8428(84)80012-8.
10
A differential effect of C5a and C5a des Arg in the induction of pulmonary inflammation.C5a与C5a去精氨酸产物在诱导肺部炎症方面的差异效应。
Am J Pathol. 1980 Jul;100(1):179-92.

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α2,6-Sialylation is Upregulated in Severe COVID-19 Implicating the Complement Cascade.α2,6-唾液酸化在重症新型冠状病毒肺炎中上调，提示补体级联反应。
medRxiv. 2022 Jun 8:2022.06.06.22275981. doi: 10.1101/2022.06.06.22275981.
2
Development of Synthetic Human and Mouse C5a: Application to Binding and Functional Assays and .合成人源和鼠源C5a的开发：在结合及功能测定中的应用 以及 。 （你提供的原文似乎不完整，最后的“and.”后面应该还有内容）
ACS Pharmacol Transl Sci. 2021 Nov 17;4(6):1808-1817. doi: 10.1021/acsptsci.1c00199. eCollection 2021 Dec 10.
3
Model structures of inactive and peptide agonist bound C5aR: Insights into agonist binding, selectivity and activation.
无活性和肽激动剂结合的C5aR的模型结构：对激动剂结合、选择性和激活的见解。
Biochem Biophys Rep. 2015 Mar 24;1:85-96. doi: 10.1016/j.bbrep.2015.03.002. eCollection 2015 May.
4
A Comparative Study of Impedance versus Optical Label-Free Systems Relative to Labelled Assays in a Predominantly Gi Coupled GPCR (C5aR) Signalling.在主要通过 Gi 偶联 GPCR（C5aR）信号传导的情况下，阻抗与光学无标记系统相对于标记测定的比较研究。
Biosensors (Basel). 2012 Jul 26;2(3):273-90. doi: 10.3390/bios2030273.
5
C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay.生理浓度的去精氨酸 C5a 通过 C5a 受体依赖性细胞激活：来自新型无标记细胞检测的见解。
J Immunol. 2012 Nov 15;189(10):4797-805. doi: 10.4049/jimmunol.1200834. Epub 2012 Oct 5.
6
Molecular analysis of the bovine anaphylatoxin C5a receptor.牛过敏毒素C5a受体的分子分析
J Leukoc Biol. 2008 Aug;84(2):537-49. doi: 10.1189/jlb.0208142. Epub 2008 May 14.
7
Role of chemotactic factors in neutrophil activation after thermal injury in rats.趋化因子在大鼠热损伤后中性粒细胞活化中的作用
Inflammation. 1999 Aug;23(4):371-85. doi: 10.1023/a:1020213717336.
8
Neutrophil adhesion to human endothelial cells is induced by the membrane attack complex: the roles of P-selectin and platelet activating factor.
Inflammation. 1998 Dec;22(6):583-98. doi: 10.1023/a:1022362413939.
9
Primary structure and functional characterization of rat C5a: an anaphylatoxin with unusually high potency.大鼠C5a的一级结构及功能特性：一种具有异常高效力的过敏毒素。
Protein Sci. 1994 Aug;3(8):1169-77. doi: 10.1002/pro.5560030803.
10
C5a-induced expression of P-selectin in endothelial cells.C5a诱导内皮细胞中P-选择素的表达。
J Clin Invest. 1994 Sep;94(3):1147-55. doi: 10.1172/JCI117430.