Evans P J, Lloyd J W, Jack T M
J R Soc Med. 1981 Nov;74(11):804-9. doi: 10.1177/014107688107401106.
Cryoanalgesia, the local application of extreme cold to nerves to produce analgesia, has been used to treat patients with intractable perineal pain. The cryoprobe was inserted percutaneously through the sacral hiatus into the sacral canal to produce anaesthesia of the lower sacral nerve roots. Forty patients received a total of 70 treatments: 31 patients (78%) were helped by the procedure and the median duration of improvement was 30 days. The treatment was more successful in relieving symptoms in patients suffering from pelvic cancer and coccydynia. The best results were obtained in those patients who received numerous freeze applications or prolonged freezing.
冷冻镇痛法，即将极冷物质局部应用于神经以产生镇痛效果，已被用于治疗顽固性会阴痛患者。将冷冻探头经皮穿过骶裂孔插入骶管，以麻醉骶神经低位神经根。40例患者共接受了70次治疗：31例患者（78%）经该治疗后症状得到缓解，改善的中位持续时间为30天。该治疗在缓解盆腔癌和尾骨痛患者的症状方面更为成功。在接受多次冷冻或长时间冷冻的患者中取得了最佳效果。
