Jungers P, Dougados M, Ganzegel C, Kremp O, Jacques C, Noel L H, Josso F
Nephrologie. 1980;1(2):67-8.
An anticoagulant with antithrombinase activity was looked for in 49 patients with systemic lupus erythematosus and found to be present in 14 of them. The latter were suffering from severe and progressive lupus, specially with arterial involvement. The presence of an isolated antithrombinase does not contraindicate a renal biopsy provided the platelet count and other coagulation factors are normal.
在49例系统性红斑狼疮患者中寻找具有抗凝血酶活性的抗凝剂,发现其中14例存在该抗凝剂。后者患有严重且进行性狼疮,特别是伴有动脉受累。如果血小板计数和其他凝血因子正常,孤立性抗凝血酶的存在并不妨碍进行肾活检。