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部分脂肪营养不良病程中伴有致密沉积物的亚临床肾小球肾炎(作者译)

[Subclinical glomerulonephritis with dense deposits in the course of partial lipodystrophy (author's transl)].

作者信息

Coulon G, Saint-Hillier Y, Hory B, Colomb H, Carbillet J P, Pageaut G, Pérol C

出版信息

Nephrologie. 1981;2(3):109-13.

PMID:7301030
Abstract

In a young woman with partial lipodystrophy accompanied by hypocomplementemia related to circulating C3NF activity, renal biopsy revealed dense deposits in the basement membranes of the glomerular capillaries without any evidence of urinary syndrome. This early form was not revealed by light microscopy and was confirmed only by ultrastructural examination. The morphological characteristics are similar to those occurring in renal grafts. The authors point out that subclinical forms of glomerulonephritis must be considered in cases of lipodystrophy and hypocomplementemia.

摘要

在一名患有部分性脂肪营养不良并伴有与循环C3NF活性相关的低补体血症的年轻女性中,肾活检显示肾小球毛细血管基底膜有致密沉积物,但无任何泌尿系统综合征的证据。这种早期形式在光学显微镜下未被发现,仅通过超微结构检查得以证实。其形态学特征与肾移植中出现的特征相似。作者指出,在脂肪营养不良和低补体血症的病例中,必须考虑肾小球肾炎的亚临床形式。

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