Terrin M, Meyer M B
Obstet Gynecol. 1981 Nov;58(5):636-8.
Perinatal mortality was examined in the Ontario Perinatal Mortality Study (1960 to 1961) subset of 31,788 births and perinatal deaths among English-speaking Canadian-born women. Overall perinatal mortality rose from 22.0 to 28.2 per 1000 if the mother smoked, a 27% increase. When perinatal mortality was computed in birth weight-specific groups (less than 2500 g and 2500 g or more), the rates for smokers were lower than those for nonsmokers in both subgroups. These results occurred because maternal smoking had an even stronger effect on birth weight than on perinatal mortality, increasing the proportion of births of infants weighing less than 2500 g by 106%. These data confirm the hazard of maternal smoking for the unborn, and pinpoint how some studies that have seemingly inconsistent results have erred in analysis.
在安大略围产期死亡率研究（1960年至1961年）中，对31788例加拿大出生的说英语的女性分娩及围产期死亡病例进行了分析。如果母亲吸烟，总体围产期死亡率从每1000例中的22.0例升至28.2例，增幅为27%。当按出生体重特定分组（小于2500克和2500克及以上）计算围产期死亡率时，两个亚组中吸烟者的死亡率均低于不吸烟者。出现这些结果的原因是，母亲吸烟对出生体重的影响比对围产期死亡率的影响更强，使体重小于2500克的婴儿出生比例增加了106%。这些数据证实了母亲吸烟对未出生胎儿的危害，并指出一些看似结果不一致的研究在分析中存在的错误。
