Linder E A
ORL J Otorhinolaryngol Relat Spec. 1981;43(6):309-13. doi: 10.1159/000275551.
Thorotrast, a contrast medium containing radioactive thorium, was in use in the period 1930 to 1945. It is retained in the body after use, with harmful effects, including the induction of malignancies. Accidental, extravasal injection during carotid angiography results in cervical granulomas with progressive, local damage. A case is reported in which lesions of the vagus, glossopharyngeal, hypoglossal and facial nerves have developed over a 40-year period after carotid angiography. A limited removal of the injected Thorotrast was carried out and, in the postoperative period, rupture of the arterial wall necessitated ligation of the common carotid artery. No additional complications arose from this. The therapeutic implications are discussed
钍造影剂，一种含有放射性钍的造影剂，在1930年至1945年期间被使用。使用后它会留在体内，产生有害影响，包括诱发恶性肿瘤。颈动脉血管造影期间意外的血管外注射会导致颈部肉芽肿，并伴有进行性局部损伤。本文报告了一例在颈动脉血管造影40年后出现迷走神经、舌咽神经、舌下神经和面神经损伤的病例。对注入的钍造影剂进行了有限的清除，术后动脉壁破裂需要结扎颈总动脉。此后未出现其他并发症。文中讨论了其治疗意义。
