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患有结肠和直肠癌的女性的卵巢切除术

Oophorectomy in women with carcinoma of the colon and rectum.

作者信息

O'Brien P H, Newton B B, Metcalf J S, Rittenbury M S

出版信息

Surg Gynecol Obstet. 1981 Dec;153(6):827-30.

PMID:7302808
Abstract

Carcinoma of the colon and rectum metastasizes readily to the ovaries, and oophorectomy during operation upon the colon and rectum remains an effective surgical technique for precluding subsequent oophorectomy and, thereby, diminishing the morbidity of carcinoma of the colon and rectum in women. This procedure does not significantly affect the survival rate. Carcinoma of the ovary has become the fourth most common lethal cancer in women. Usually, the tumor is diagnosed after the development of ascites, mass and weight loss. The five year survival rate remains about 30 per cent. The incidence of carcinoma of the ovary in women with carcinoma of the colon and rectum is roughly five times the incidence of carcinoma of the ovary, that would be expected by chance. We believe the aforementioned observations strongly expand and reinforce the original proponents of prophylactic oophorectomy performed upon women with carcinoma of the colon and rectum and that, therefore, oophorectomy should be an integral part of operation upon the colon and rectum in women.

摘要

结肠和直肠癌很容易转移至卵巢,在结肠和直肠手术中进行卵巢切除术仍然是一种有效的外科技术,可避免后续的卵巢切除术,从而降低女性结肠和直肠癌的发病率。该手术对生存率没有显著影响。卵巢癌已成为女性第四大常见致命癌症。通常,肿瘤在出现腹水、肿块和体重减轻后才被诊断出来。五年生存率仍约为30%。结肠和直肠癌女性患者中卵巢癌的发病率大约是偶然预期的卵巢癌发病率的五倍。我们认为,上述观察结果有力地扩展和强化了对结肠和直肠癌女性患者进行预防性卵巢切除术的最初支持者的观点,因此,卵巢切除术应成为女性结肠和直肠手术的一个组成部分。

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