Zimmermann E, Pölz E
Wien Klin Wochenschr. 1981 Sep 4;93(16):519-21.
Transport kinetics of urea and creatinine across the cell wall was investigated on the model of azotaemic erythrocytes. Urea was found to pass rapidly across the cell membrane whilst the transport of creatinine is delayed to a calculated half time of approximately 12 minutes. Transport of metabolites play an important role in dialysis efficacy. the significance of transcellular transport kinetics of different molecules with respect to dialysis strategy is discussed.
在氮血症红细胞模型上研究了尿素和肌酐跨细胞壁的转运动力学。发现尿素能快速穿过细胞膜，而肌酐的转运延迟至计算得出的约12分钟的半衰期。代谢物的转运在透析效果中起重要作用。讨论了不同分子的跨细胞转运动力学对于透析策略的意义。
