[Quantitative determination of immunoglobulins in chronic obstructive bronchitis].

In a systematic series of examination the quantitative determination of the immunoglobulin IgG, IgA and IgM in patients with advanced chronic obstructive bronchitis and formation of emphysemas was performed without a spastic component. In the result is to be stated: 1. a highly significant increase of the IgA concentration, 2, a significant decrease of the IgG-concentration, 3. no change of the IgM-concentration. Thus the IgA shows the behaviour known in chronic unspecific inflammation of the bronchial wall. The decrease of IgG proved might be an expression of a general decreased function of the organ due to a chronic hypoxia. The results show that there are apparently no relation between the IgM-concentration in the serum and the chronic obstructive bronchitis.