Voigt T, Voigt H, Wegner H, Scheel H
Z Gesamte Inn Med. 1981 Jun 15;36(12):418-21.
IN general the therapy of thrombosis during pregnancy is carried out with heparin, in which case the initial hospital treatment may be continued later on with double subcutaneous applications of heparin in the out-patient department. Apart from coagulation-physiological parameters plethysmography and/or ultrasound Doppler method serve for the control of the course. Within the prophylaxis of recidivations in earlier thromboembolism during pregnancy regular clinical and apparative controls are performed, in which cases in the last third of the pregnancy the possibilities of the consideration work are used. Immediately pre-, intra- and postpartally heparin is injected with low dose up to the optimum phenprokoumon regulation (beginning with the 2nd day post partum). Thromboses in the anamnesis are no essential risk, when an optimum prophylaxis of thrombosis is guaranteed during pregnancy and puerperium
一般来说,孕期血栓形成的治疗采用肝素,在这种情况下,最初的住院治疗之后可在门诊继续进行肝素皮下双次注射。除了凝血生理参数外,体积描记法和/或超声多普勒法可用于监测病程。对于孕期早期血栓栓塞复发的预防,要进行定期的临床和仪器检查,在妊娠晚期要利用相关的检查手段。在临产前、产时和产后立即注射低剂量肝素,直至达到苯丙香豆素的最佳调节状态(从产后第2天开始)。如果在孕期和产褥期能保证最佳的血栓形成预防措施,既往有血栓形成病史并非主要风险。