Leitsmann H, Prager W
Zentralbl Gynakol. 1981;103(17):1004-13.
Various diagnostic methods, generally suitable for early diagnosis of carcinoma recurrence, were used in a systematic localised search programme on 799 patients with invasive cervical carcinoma. The practicability of a concept for early detection of recurrence was verified and established by shortening of latency from first manifestation to recurrence and by more frequent detection of recurrent processes even without symptoms. Reported are methods selected from the programme for their suitability for early recurrence detection. These were necessarily restricted to detection of localised recurrence, following radiological or combined treatment, whereas early detection of parametrial and pelvic wall recurrences seemed to be purposeful, too, when preceded exclusively by primary surgical therapy. Rates of survival, following at least one year of recurrence observation, were encouraging and the support of the view that early detection of recurrence might help to improve the chance of healing.
针对799例浸润性宫颈癌患者,在一项系统性局部检查项目中采用了多种通常适用于早期诊断癌症复发的诊断方法。通过缩短从首次出现症状到复发的潜伏期,以及更频繁地检测到即使无症状的复发过程,验证并确立了一种早期检测复发概念的实用性。报告了从该项目中选出的因其适用于早期复发检测的方法。这些方法必然仅限于检测放疗或综合治疗后的局部复发,而当仅先行一期手术治疗时,对宫旁和盆腔壁复发的早期检测似乎也很有意义。在对复发进行至少一年的观察之后,生存率令人鼓舞,这支持了早期检测复发可能有助于提高治愈几率这一观点。