Roper-Drewinko P R, Drewinko B, Corrigan G, Johnston D, McCredie K B, Freireich E J
Am J Hematol. 1981 Sep;11(2):183-203. doi: 10.1002/ajh.2830110210.
Methods for the standardization of several currently used platelet function tests (bleeding time, capillary fragility, platelet retention, platelet aggregation, platelet factor 3, and platelet volume profiles) are presented, Different variables than may interfere with the reproducibility of the results of each assay were identified and standardized. Using the standardized techniques, the range of normal values for each test was determined in a large population of normal volunteers and used to identify disease states by comparing patient results with those of the normal population. A format for presenting the entire profile of platelet function parameters is proposed.
介绍了几种目前常用的血小板功能测试(出血时间、毛细血管脆性、血小板滞留、血小板聚集、血小板因子3和血小板体积分布)的标准化方法。识别并标准化了可能干扰每种检测结果可重复性的不同变量。使用标准化技术,在大量正常志愿者中确定了每项测试的正常价值范围,并通过将患者结果与正常人群结果进行比较来识别疾病状态。提出了一种呈现血小板功能参数全貌的格式。