Wilkening M, Lassaunière J M, Freysz M, Foissac J C, Weiller J, Roulet J J, Honnart D
Anesth Analg (Paris). 1981;38(7-8):365-8.
This work analyzes the results of 88 blocks for intractable pain in thoracic and abdominal malignant diseases. Results and duration of analgesia are compared in regard to the localization of pain and to the use of alcohol or phenol. Best analgesic results are obtained in the pelvic pains and especially in the colorectal pains. The analgesic results and the duration of analgesia are poorer since the spinal nerves to block are higher, there are only 50 p. cent of good results in the thoracic region. Analgesic results are the same with alcohol or phenol, but duration of analgesia seems to be longer with phenol. The two routes of administration, subarachnoid or epidural, seem to give equal results. Motor paralysis of the bladder or the rectum may occur, especially in the low pelvic localizations and these complications justify careful selection of the indication.
这项研究分析了88例胸腹部恶性疾病顽固性疼痛患者的治疗结果。根据疼痛部位以及酒精或苯酚的使用情况，对镇痛效果和持续时间进行了比较。盆腔疼痛尤其是结肠直肠疼痛的镇痛效果最佳。由于要阻滞的脊神经位置较高，镇痛效果和持续时间较差，在胸部区域仅有50%的患者获得良好效果。酒精和苯酚的镇痛效果相同，但苯酚的镇痛持续时间似乎更长。蛛网膜下腔或硬膜外两种给药途径的效果似乎相当。膀胱或直肠运动麻痹可能会发生，尤其是在盆腔低位部位，这些并发症说明需要谨慎选择适应证。
