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评估仪器化测力平台作为测量麻醉残留效应的一项测试。

Evaluation of instrumented force platform as a test to measure residual effects of anesthetics.

作者信息

Korttila K, Ghoneim M M, Jacobs L, Lakes R S

出版信息

Anesthesiology. 1981 Dec;55(6):625-30. doi: 10.1097/00000542-198155060-00004.

Abstract

Recovery from anesthesia was assessed in a controlled manner in 38 healthy student volunteers, using two psychomotor tests (perceptual speed and tapping board) and an instrumented force platform 1, 3, 5 and 7 h after intravenous injection of 0.3 mg/kg diazepam, 2.0 mg/kg methohexital, 6.0 mg/kg thiopental or saline. Postural stability remained unaltered but the performance on psychomotor tests improved when the tests were repeated after saline injection. Methohexital did not induce any changes in body sway or psychomotor performance at the time periods tested when compared with saline. Postural stability of subjects receiving thiopental or diazepam was imparied (P less than 0.001) for 1 and 7 hours after anesthesia, respectively, when compared with saline. The impairment on performance in the psychomotor tests induced by thiopental or diazepam was of smaller magnitude and for diazepam of shorter duration than balance disturbances measured with the body sway tests. Further clinical studies on the use of the instrumented force platform as a fast and easily interpretable guideline for discharge from hospital after different modes of outpatient anesthesia are warranted.

摘要

在38名健康学生志愿者中,以对照方式评估麻醉恢复情况。在静脉注射0.3mg/kg地西泮、2.0mg/kg美索比妥、6.0mg/kg硫喷妥钠或生理盐水后1、3、5和7小时,使用两项心理运动测试(感知速度和敲击板)和一个仪器化测力平台进行评估。姿势稳定性未发生改变,但注射生理盐水后重复测试时,心理运动测试的表现有所改善。与生理盐水相比,在测试时间段内,美索比妥未引起身体摆动或心理运动表现的任何变化。与生理盐水相比,接受硫喷妥钠或地西泮的受试者在麻醉后1小时和7小时的姿势稳定性分别受损(P<0.001)。硫喷妥钠或地西泮引起的心理运动测试表现受损程度较小,地西泮的持续时间比身体摆动测试所测量的平衡障碍持续时间短。有必要进一步开展临床研究,以确定将仪器化测力平台作为不同门诊麻醉方式后出院的快速且易于解读的指导标准。

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