在插管新生儿中使用外部呼气阻力以增加肺容积。
Use of external expiratory resistance in intubated neonates to increase lung volume.
作者信息
Moomjian A S, Schwartz J G, Shutack J G, Rooklin A R, Shaffer T H, Fox W W
出版信息
Arch Dis Child. 1981 Nov;56(11):869-73. doi: 10.1136/adc.56.11.869.
Ten intubated neonates (weights 0.90 to 2.58 kg) recovering from respiratory disease had lung mechanics, respiratory patterns, and functional residual capacity measured at 0 cmH2O continuous positive airways pressure and then after application of serially increasing levels of external expiratory resistance. At an external expiratory resistance greater than 40 cmH2O/1 per second, there was a significant increase in mean functional residual capacity compared with control levels. Immediately after the application of external expiratory resistance, there was a significant decrease in flow which returned to control values after a few breaths. Tidal volume and respiratory rate decreased for a few breaths after the application of the external expiratory resistance, but returned to control values after several seconds. Study age, gestational age, or study weight had no appreciable effect on the relationship between functional residual capacity and external expiratory resistance. Application of external expiratory resistance may be useful for stabilising lung volume in neonates recovering from respiratory disease.
十名从呼吸道疾病中康复的插管新生儿（体重0.90至2.58千克），在气道持续正压为0厘米水柱时测量其肺力学、呼吸模式和功能残气量，然后在依次增加外部呼气阻力水平后再次测量。当外部呼气阻力大于40厘米水柱/每秒时，平均功能残气量与对照水平相比显著增加。施加外部呼气阻力后，气流立即显著下降，数呼吸后恢复到对照值。施加外部呼气阻力后，潮气量和呼吸频率在数呼吸内下降，但数秒后恢复到对照值。研究年龄、胎龄或研究体重对功能残气量与外部呼气阻力之间的关系没有明显影响。施加外部呼气阻力可能有助于稳定从呼吸道疾病中康复的新生儿的肺容量。
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