Hanel K C, Abbott W M, Reidy N C, Fulchino D, Miller A, Brewster D C, Athanasoulis C A
Ann Surg. 1981 Dec;194(6):725-30. doi: 10.1097/00000658-198112000-00011.
A prospective study was performed to evaluate the accuracy and usefulness of two noninvasive modalities, Doppler ultrasonography and segmental air plethysmography, in the detection of deep vein thrombosis. Over a two-year period, 211 limbs were studied among 167 patients, and the results were compared with venography. Doppler ultrasonography was found to be very accurate in detecting above-knee thrombi (sensitivity: 92.4%, specificity: 90.7%) while plethysmography was found to be much less accurate (sensitivity: 77.3%, specificity: 62.4%). The results were also assessed according to the mode of patient presentation. Doppler ultrasonography was found to be very useful in symptomatic out-patients, because of the lower incidence of calf thrombi, and less accurate in symptomatic inpatients and in high risk in-patients being screened. The clinical usefulness of noninvasive detection of venous thrombosis is discussed with regard to the incidence of disease and the site of thrombosis in different patient groups under study, and recommendations are made based on these results.
进行了一项前瞻性研究，以评估两种非侵入性检查方法，即多普勒超声检查和节段性肢体容积描记法，在检测深静脉血栓形成方面的准确性和实用性。在两年时间里，对167例患者的211条肢体进行了研究，并将结果与静脉造影进行了比较。结果发现，多普勒超声检查在检测膝上血栓方面非常准确（敏感性：92.4%，特异性：90.7%），而肢体容积描记法的准确性则低得多（敏感性：77.3%，特异性：62.4%）。还根据患者的就诊方式对结果进行了评估。由于小腿血栓的发生率较低，多普勒超声检查在有症状的门诊患者中非常有用，而在有症状的住院患者和接受筛查的高危住院患者中准确性较低。结合所研究的不同患者群体中疾病的发生率和血栓形成的部位，讨论了静脉血栓形成非侵入性检测的临床实用性，并根据这些结果提出了建议。
