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[免疫球蛋白外壳在微生物吞噬过程中的作用]

[Role of the immunoglobulin coat in the process of microorganism phagocytosis].

作者信息

Bykov A S, Lazurenko I S, Seleznev A S

出版信息

Arkh Patol. 1981;43(9):10-6.

PMID:7305673
Abstract

Comparative electron microscopic examinations of staphylococcus aureus under different conditions (in a pulmonary abscess of a patient, in a short-time contact with serum and blood cells of a donor, and experimental infection of white mice) revealed dissimilar possibilities of formation of an immunoglobulin coat on the surface of bacterial cell wall. Upon a short-time contact of S. aureus with human blood serum in vitro an immunoglobulin coating appeared on the bacterial cell wall. In control experiments with staphylococci killed with glutaraldehyde and treated with methycilline the possibility of formation of microcapsule by staphylococci was excluded. No immunoglobulin coating was detected in a protracted suppurative process. In the pulmonary abscess, different gram-positive and gram-negative bacteria were found.

摘要

对金黄色葡萄球菌在不同条件下(患者肺脓肿中、与供体血清和血细胞短时间接触以及对小白鼠进行实验性感染)进行的比较电子显微镜检查显示,在细菌细胞壁表面形成免疫球蛋白包被的可能性不同。在体外金黄色葡萄球菌与人血清短时间接触后,细菌细胞壁上出现了免疫球蛋白包被。在用戊二醛杀死并用甲氧西林处理的葡萄球菌的对照实验中,排除了葡萄球菌形成微荚膜的可能性。在长期化脓过程中未检测到免疫球蛋白包被。在肺脓肿中,发现了不同的革兰氏阳性和革兰氏阴性细菌。

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