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大鼠中枢神经系统髓磷脂的UDP-半乳糖:神经酰胺半乳糖基转移酶

UDP-galactose:ceramide galactosyltransferase of rat central-nervous-system myelin.

作者信息

Koul O, Jungalwala F B

出版信息

Biochem J. 1981 Feb 15;194(2):633-7. doi: 10.1042/bj1940633.

Abstract

The properties of ceramide galactosyltransferase associated with myelin and microsomal fractions of rat brain were studied. The enzyme from both the fractions had similar properties during development and synthesized the same molecular species of the product cerebroside. The results suggested that during myelination the turnover rate of enzyme protein is altered instead of regulatory modulation of the enzyme protein.

摘要

对与大鼠脑髓鞘和微粒体部分相关的神经酰胺半乳糖基转移酶的特性进行了研究。来自这两个部分的酶在发育过程中具有相似的特性,并合成了相同分子种类的产物脑苷脂。结果表明,在髓鞘形成过程中,酶蛋白的周转率发生了改变,而不是对酶蛋白进行调节性调控。

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Effect of exogenous lipids on membrane-bound ceramide glycosyltransferases of rat brain.
Arch Biochem Biophys. 1975 Apr;167(2):646-54. doi: 10.1016/0003-9861(75)90508-1.

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