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Different pathways of iodothyronine 5'-deiodination in rat cerebral cortex.

作者信息

Visser T J, Leonard J L, Kaplan M M, Larsen P R

出版信息

Biochem Biophys Res Commun. 1981 Aug 31;101(4):1297-304. doi: 10.1016/0006-291x(81)91588-6.

DOI:10.1016/0006-291x(81)91588-6
PMID:7306134
Abstract
摘要

相似文献

1
Different pathways of iodothyronine 5'-deiodination in rat cerebral cortex.大鼠大脑皮层中碘甲状腺原氨酸5'-脱碘的不同途径。
Biochem Biophys Res Commun. 1981 Aug 31;101(4):1297-304. doi: 10.1016/0006-291x(81)91588-6.
2
Evidence for two pathways of iodothyronine 5'-deiodination in rat pituitary that differ in kinetics, propylthiouracil sensitivity, and response to hypothyroidism.大鼠垂体中存在两种碘甲状腺原氨酸5'-脱碘途径的证据，这两种途径在动力学、丙硫氧嘧啶敏感性及对甲状腺功能减退的反应方面存在差异。
J Clin Invest. 1983 Apr;71(4):992-1002. doi: 10.1172/jci110854.
3
Kinetic evidence suggesting two mechanisms for iodothyronine 5'-deiodination in rat cerebral cortex.动力学证据表明大鼠大脑皮层中碘甲状腺原氨酸5'-脱碘存在两种机制。
Proc Natl Acad Sci U S A. 1982 Aug;79(16):5080-4. doi: 10.1073/pnas.79.16.5080.
4
Characteristics of iodothyronine tyrosyl ring deiodination by rat cerebral cortical microsomes.大鼠大脑皮质微粒体对碘甲状腺原氨酸酪氨酸环脱碘作用的特征
Endocrinology. 1983 Jan;112(1):35-42. doi: 10.1210/endo-112-1-35.
5
Evidence for two tissue-specific pathways for in vivo thyroxine 5'-deiodination in the rat.大鼠体内甲状腺素5'-脱碘作用存在两条组织特异性途径的证据。
J Clin Invest. 1982 May;69(5):1176-84. doi: 10.1172/jci110554.
6
Regulation of iodothyronine deiodinase activity as studied in thyroidectomized rats infused with thyroxine or triiodothyronine.在甲状腺切除并用甲状腺素或三碘甲状腺原氨酸灌注的大鼠中对碘甲状腺原氨酸脱碘酶活性的调节研究。
Endocrinology. 1997 Jun;138(6):2559-68. doi: 10.1210/endo.138.6.5212.
7
Deiodination of thyroid hormones by the perfused rat liver.灌注大鼠肝脏对甲状腺激素的脱碘作用。
J Physiol. 1972 Apr;222(2):475-85. doi: 10.1113/jphysiol.1972.sp009809.
8
Concomitant decrease of the effects of thyroxin on TRH-induced TSH release, and of the pituitary content of triiodothyronine in animals on propylthiouracil.丙硫氧嘧啶处理的动物中，甲状腺素对促甲状腺激素释放激素诱导的促甲状腺激素释放作用以及垂体三碘甲状腺原氨酸含量同时降低。
Endocrinology. 1974 Sep;95(3):916-21. doi: 10.1210/endo-95-3-916.
9
Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone.丙硫氧嘧啶抑制L-甲状腺素转化为L-三碘甲状腺原氨酸。对丙硫氧嘧啶的抗甲状腺素作用的解释以及支持三碘甲状腺原氨酸是活性甲状腺激素这一概念的证据。
J Clin Invest. 1972 Sep;51(9):2493-7. doi: 10.1172/JCI107063.
10
Sequential deiodination of thyroxine in rat liver homogenate.大鼠肝脏匀浆中甲状腺素的顺序脱碘作用。
Biochem J. 1978 Jul 15;174(1):221-9. doi: 10.1042/bj1740221.

引用本文的文献

1
Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.酶促卤化和脱卤反应：普遍存在且机制多样。
Chem Rev. 2017 Apr 26;117(8):5619-5674. doi: 10.1021/acs.chemrev.6b00571. Epub 2017 Jan 20.
2
Development of thyroxine type II deiodinase activity in brains of Zucker rats.Zucker大鼠大脑中II型甲状腺素脱碘酶活性的发育
Biochem J. 1994 Nov 15;304 ( Pt 1)(Pt 1):259-61. doi: 10.1042/bj3040259.
3
Iodothyronine deiodinase activity in methionine-deficient rats fed selenium-deficient or selenium-sufficient diets.
在喂食缺硒或富硒日粮的蛋氨酸缺乏大鼠体内的碘甲状腺原氨酸脱碘酶活性。
Biol Trace Elem Res. 1995 May;48(2):197-213. doi: 10.1007/BF02789192.
4
Evidence for two tissue-specific pathways for in vivo thyroxine 5'-deiodination in the rat.大鼠体内甲状腺素5'-脱碘作用存在两条组织特异性途径的证据。
J Clin Invest. 1982 May;69(5):1176-84. doi: 10.1172/jci110554.
5
Kinetic evidence suggesting two mechanisms for iodothyronine 5'-deiodination in rat cerebral cortex.动力学证据表明大鼠大脑皮层中碘甲状腺原氨酸5'-脱碘存在两种机制。
Proc Natl Acad Sci U S A. 1982 Aug;79(16):5080-4. doi: 10.1073/pnas.79.16.5080.
6
Evidence for two pathways of iodothyronine 5'-deiodination in rat pituitary that differ in kinetics, propylthiouracil sensitivity, and response to hypothyroidism.大鼠垂体中存在两种碘甲状腺原氨酸5'-脱碘途径的证据，这两种途径在动力学、丙硫氧嘧啶敏感性及对甲状腺功能减退的反应方面存在差异。
J Clin Invest. 1983 Apr;71(4):992-1002. doi: 10.1172/jci110854.
7
Comparison of iodothyronine 5'-deiodinase and other thyroid-hormone-dependent enzyme activities in the cerebral cortex of hypothyroid neonatal rat. Evidence for adaptation to hypothyroidism.甲状腺功能减退新生大鼠大脑皮质中碘甲腺原氨酸5'-脱碘酶及其他甲状腺激素依赖性酶活性的比较。适应甲状腺功能减退的证据。
J Clin Invest. 1982 Nov;70(5):1110-23. doi: 10.1172/jci110699.
8
Potential of brown adipose tissue type II thyroxine 5'-deiodinase as a local and systemic source of triiodothyronine in rats.大鼠棕色脂肪组织II型甲状腺素5'-脱碘酶作为三碘甲状腺原氨酸局部和全身来源的潜力。
J Clin Invest. 1985 Dec;76(6):2296-305. doi: 10.1172/JCI112239.
9
Iodothyronine deiodination in the brain of diabetic rats: influence of thyroid status.糖尿病大鼠脑内碘甲状腺原氨酸脱碘作用：甲状腺状态的影响。
J Endocrinol Invest. 1986 Apr;9(2):127-33. doi: 10.1007/BF03348082.
10
Regulation of thyroid-stimulating hormone (TSH) secretion in the fetus and neonate.胎儿和新生儿促甲状腺激素（TSH）分泌的调节。
J Endocrinol Invest. 1988 Feb;11(2):145-58. doi: 10.1007/BF03350124.