Hankoff L D, Peress N S
Biol Psychiatry. 1981 Oct;16(10):945-52.
The brain stem was examined in a series of 27 autopsy cases for a possible association of microscopic changes and primary psychiatric disorder. Seven cases were found to have brain stem microglial nodules or perivascular infiltrates in association with a range of CNS pathological conditions. One of eight schizophrenic and none of four primary affective disorder patients showed brain stem pathology. While evident in many forms of coarse brain disease, brain stem microscopic changes do not appear related to primary psychiatric disorder.
在27例尸检病例中检查脑干,以探寻微观变化与原发性精神障碍之间可能存在的关联。发现7例存在脑干小胶质结节或血管周围浸润,并伴有一系列中枢神经系统病理状况。8例精神分裂症患者中有1例,4例原发性情感障碍患者中无一例显示有脑干病变。虽然脑干微观变化在多种严重脑部疾病中很明显,但似乎与原发性精神障碍无关。