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Rotation of sickle cells in homogeneous magnetic fields.镰状细胞在均匀磁场中的旋转。
Biophys J. 1981 Nov;36(2):443-7. doi: 10.1016/S0006-3495(81)84743-1.
2
Two-step mechanism of homogeneous nucleation of sickle cell hemoglobin polymers.镰状细胞血红蛋白聚合物均相成核的两步机制。
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Analysis of the intermolecular contacts within sickle hemoglobin fibers: effect of site-specific substitutions, fiber pitch, and double-strand disorder.镰状血红蛋白纤维内分子间接触的分析:位点特异性取代、纤维螺距和双链无序的影响
J Struct Biol. 1993 Nov-Dec;111(3):161-79. doi: 10.1006/jsbi.1993.1047.
4
Evaluation of the water environments in deoxygenated sickle cells by longitudinal and transverse water proton relaxation rates.通过纵向和横向水质子弛豫率评估脱氧镰状细胞中的水环境。
Arch Biochem Biophys. 1975 Jan;166(1):193-200. doi: 10.1016/0003-9861(75)90380-x.
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Sickle-cell haemoglobin polymerization: is it the primary pathogenic event of sickle-cell anaemia?镰状细胞血红蛋白聚合:它是镰状细胞贫血的主要致病事件吗?
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Anisotropy in sickle hemoglobin fibers from variations in bending and twist.镰状血红蛋白纤维因弯曲和扭转变化而产生的各向异性。
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Computer models of a new deoxy-sickle cell hemoglobin fiber based on x-ray diffraction data.基于X射线衍射数据的新型脱氧镰状细胞血红蛋白纤维的计算机模型。
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A rapid paper-based test for quantifying sickle hemoglobin in blood samples from patients with sickle cell disease.一种用于定量镰状细胞病患者血样中镰状血红蛋白的快速纸质检测方法。
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[Hemoglobin S as the cause of primary hyperviscosity of the blood].[血红蛋白S作为血液原发性高黏滞度的病因]
Ric Clin Lab. 1983;13 Suppl 3:115-20.

引用本文的文献

1
[Clinical high- and ultrahigh-field MR and its interaction with biological systems].[临床高场和超高场磁共振成像及其与生物系统的相互作用]
Radiologe. 2004 Jan;44(1):19-30. doi: 10.1007/s00117-003-0993-5.
2
Magnetic alignment of collagen during self-assembly.自组装过程中胶原蛋白的磁性排列。
Biochem J. 1984 May 1;219(3):1057-9. doi: 10.1042/bj2191057.
3
Effects of an inhomogeneous magnetic field on flowing erythrocytes.非均匀磁场对流动红细胞的影响。
Eur Biophys J. 1987;14(3):139-45. doi: 10.1007/BF00253838.

本文引用的文献

1
ON THE MAGNETIC ASYMMETRY OF MUSCLE FIBERS.论肌纤维的磁不对称性。
Proc Natl Acad Sci U S A. 1958 Jan;44(1):1-4. doi: 10.1073/pnas.44.1.1.
2
The Magnetic Properties and Structure of Hemoglobin, Oxyhemoglobin and Carbonmonoxyhemoglobin.血红蛋白、氧合血红蛋白和碳氧血红蛋白的磁性与结构
Proc Natl Acad Sci U S A. 1936 Apr;22(4):210-6. doi: 10.1073/pnas.22.4.210.
3
Electron microscope study of the kinetics of the fiber-to-crystal transition of sickle cell hemoglobin.镰状细胞血红蛋白纤维到晶体转变动力学的电子显微镜研究。
Proc Natl Acad Sci U S A. 1980 Feb;77(2):944-8. doi: 10.1073/pnas.77.2.944.
4
Molecular mechanism of red cell "sickling".红细胞“镰变”的分子机制
Science. 1966 Jul 8;153(3732):145-9. doi: 10.1126/science.153.3732.145.
5
Magnetic anisotropy and the orientation of retinal rods in a homogeneous magnetic field.均匀磁场中视网膜视杆细胞的磁各向异性与取向
Proc Natl Acad Sci U S A. 1971 Jun;68(6):1283-5. doi: 10.1073/pnas.68.6.1283.
6
[Rotation of external segments of photoreceptors in constant magnetic field].[恒定磁场中光感受器外节的旋转]
C R Acad Hebd Seances Acad Sci D. 1970 Jul 6;271(1):130-3.
7
Structure of hemoglobin S fibers: optical determination of the molecular orientation in sickled erythrocytes.血红蛋白 S 纤维的结构:镰状红细胞中分子取向的光学测定
Proc Natl Acad Sci U S A. 1973 Dec;70(12):3604-8. doi: 10.1073/pnas.70.12.3604.
8
Paramagnetic anisotropy measurements on a single crystal of deoxyhemoglobin.对脱氧血红蛋白单晶进行的顺磁各向异性测量。
Biochim Biophys Acta. 1972 Sep 29;278(2):355-71. doi: 10.1016/0005-2795(72)90240-1.
9
Crystal structure of sickle-cell deoxyhemoglobin at 5 A resolution.分辨率为5埃的镰状细胞脱氧血红蛋白晶体结构。
J Mol Biol. 1975 Oct 15;98(1):179-94. doi: 10.1016/s0022-2836(75)80108-2.
10
The Protein Data Bank: a computer-based archival file for macromolecular structures.蛋白质数据库:一个基于计算机的大分子结构存档文件。
J Mol Biol. 1977 May 25;112(3):535-42. doi: 10.1016/s0022-2836(77)80200-3.

镰状细胞在均匀磁场中的旋转。

Rotation of sickle cells in homogeneous magnetic fields.

作者信息

Riberiro P C, Davidovich M A, Wajnberg E, Bemski G, Kischinevsky M

出版信息

Biophys J. 1981 Nov;36(2):443-7. doi: 10.1016/S0006-3495(81)84743-1.

DOI:10.1016/S0006-3495(81)84743-1
PMID:7306665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1327607/
Abstract

Deoxygenated sickle cells (HbS) have been shown to orient in homogeneous magnetic fields because of magnetic anisotropy of the hemes. The time of rotation is proportional to 1/H2 and is in agreement with theory. Structural information concerning the orientation of HbS molecules in the fibers is obtained from these experiments and is shown to agree substantially with existing models.

摘要

由于血红素的磁各向异性,已证明脱氧镰状细胞(HbS)在均匀磁场中会发生取向。旋转时间与1/H²成正比,且与理论相符。从这些实验中获得了有关纤维中HbS分子取向的结构信息,结果表明与现有模型基本一致。