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龟视网膜的水平细胞。I. 高尔基染色制剂的光学显微镜观察

Horizontal cells of the turtle retina. I. Light microscopy of Golgi preparations.

作者信息

Leeper H F

出版信息

J Comp Neurol. 1978 Dec 15;182(4 Pt 2):777-93. doi: 10.1002/cne.901820503.

DOI:10.1002/cne.901820503
PMID:730847
Abstract

In Golgi preparations of turtle retina, four types of horizontal cells were observed and their morphological characteristics determined in vertical thick sections, whole mount preparations, and reconstructions from serial 1-micrometer sections. H1 consists of a nucleated, stellate cell body (H1CB) and an irregular, tuberous axon terminal (H1AT) connected by a slender axon. Both parts of these cells make contact with receptor cells. H1CB's appear to correspond to "L2-type cells" while H1AT's correspond to "L1-type cells" described in the physiological literature. H2 and H3 are axonless stellate cells which are similar to one another in vertical profile and may occasionally appear similar in horizontal view. In general, the dendritic tree is more densely branched and the density of receptor cell contacts is higher for H2 than for H3. H2-type cells may correspond to "R/G C-type cells." H4 is also an axonless stellate cell type which is smaller than H2 or H3 at equivalent retinal locations. The dendritic fields of H1CB's vary widely, but systematically, in size and shape over the retina. Their size is inversely related to receptor cell density, and the shape of the dendritic tree varies from roughly circular in the central area to elliptical in the periphery of the retina.

摘要

在乌龟视网膜的高尔基氏染色标本中,观察到四种水平细胞,并在垂直厚切片、整装标本以及连续1微米切片的重建标本中确定了它们的形态特征。H1由一个有核的星状细胞体(H1CB)和一个通过细长轴突连接的不规则结节状轴突终末(H1AT)组成。这些细胞的两个部分都与受体细胞接触。H1CB似乎对应于生理学文献中描述的“L2型细胞”,而H1AT对应于“L1型细胞”。H2和H3是无轴突的星状细胞,它们在垂直轮廓上彼此相似,在水平视图中偶尔也可能看起来相似。一般来说,H2的树突分支比H3更密集,且与受体细胞的接触密度更高。H2型细胞可能对应于“R/G C型细胞”。H4也是一种无轴突的星状细胞类型,在视网膜的等效位置上比H2或H3小。H1CB的树突野在视网膜上的大小和形状差异很大,但具有系统性。它们的大小与受体细胞密度成反比,树突的形状从视网膜中央区域的大致圆形到周边区域的椭圆形不等。

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引用本文的文献

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Diverse Cell Types, Circuits, and Mechanisms for Color Vision in the Vertebrate Retina.脊椎动物视网膜中用于颜色视觉的多种细胞类型、回路和机制。
Physiol Rev. 2019 Jul 1;99(3):1527-1573. doi: 10.1152/physrev.00027.2018.
2
Horizontal Cells, the Odd Ones Out in the Retina, Give Insights into Development and Disease.水平细胞是视网膜中的异类,为发育和疾病研究提供了线索。
Front Neuroanat. 2016 Jul 19;10:77. doi: 10.3389/fnana.2016.00077. eCollection 2016.
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Specificity of the horizontal cell-photoreceptor connections in the zebrafish (Danio rerio) retina.
斑马鱼(Danio rerio)视网膜中水平细胞与光感受器连接的特异性。
J Comp Neurol. 2009 Oct 10;516(5):442-53. doi: 10.1002/cne.22135.
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Morphology of horizontal cells in the frog retina.青蛙视网膜水平细胞的形态学
Cell Tissue Res. 1981;221(2):443-9. doi: 10.1007/BF00216747.
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Involvement of small-field horizontal cells in feedback effects on green cones of turtle retina.小视野水平细胞对龟视网膜绿锥细胞的反馈作用
Proc Natl Acad Sci U S A. 1981 Jul;78(7):4616-9. doi: 10.1073/pnas.78.7.4616.
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J Gen Physiol. 1985 Sep;86(3):423-53. doi: 10.1085/jgp.86.3.423.
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