氨鲁米特——一种用于乳腺癌后续治疗的新药
[Aminoglutethimide - a new drug for the after care in breast cancer].
作者信息
Rabe T, Rabe D, Runnebaum B
出版信息
Fortschr Med. 1981 Nov 19;99(43):1816-8.
PMID:7308944
Abstract
Aminoglutethimide is an inhibitor of various steroid hydroxylation reactions in the adrenal gland, the ovary, the testis and the placenta; furthermore, the extraglandular estrogen synthesis is inhibited by blocking the aromatase in the subcutaneous fatty tissue.
摘要
氨鲁米特是肾上腺、卵巢、睾丸和胎盘各种类固醇羟基化反应的抑制剂；此外，通过阻断皮下脂肪组织中的芳香化酶来抑制腺外雌激素的合成。
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