Häring M
Fortschr Med. 1981 Nov 26;99(44):1858-62.
Experiments were carried out on 12 weeks old dogs to determine the reaction of the proximal tibial epiphysis to different implants. The contralateral tibial epiphysis was used as controls. As implants we used Kirschner wires, medullary nails, screws and miniplates, which were inserted through the epiphyseal plate itself. The further development of the epiphysis was followed till completion of growth. The changes observed were proportional to the pressure exerted by the implant and reached from reversible lesions to premature ossification with faulty growth.