St John R, Timney B
Invest Ophthalmol Vis Sci. 1981 Dec;21(6):873-7.
There is both anatomical and electrophysiological evidence that human albinos have abnormally crossed visual pathways. The present study examined some perceptual consequences of such pathways on the visual abilities of 12 oculocutaneous albinos and one ocular albino. Measurements were made of visual fields in all subjects. For seven subjects, contrast sensitivity functions were obtained for the central, nasal, and temporal retinas. There was a wide variation in the dimensions of the visual fields, but there was no evidence for a loss corresponding to the origin of the aberrant projections. On the basis of their contrast sensitivity functions, however, it was possible to classify the albinos into two groups. One group, with higher overall sensitivity, showed no differences between central, nasal, and temporal retina. The other group showed a marked depression in sensitivity for the temporal retina, indicating that in some albinos, information from the retinal region corresponding to the aberrant pathway is degraded.
有解剖学和电生理学证据表明，人类白化病患者的视觉通路存在异常交叉。本研究考察了这种通路对12名眼皮肤白化病患者和1名眼部白化病患者视觉能力的一些感知后果。对所有受试者进行了视野测量。对7名受试者，获取了中央、鼻侧和颞侧视网膜的对比敏感度函数。视野大小存在很大差异，但没有证据表明与异常投射起源相对应的区域存在视野缺损。然而，根据他们的对比敏感度函数，可以将白化病患者分为两组。一组总体敏感度较高，中央、鼻侧和颞侧视网膜之间没有差异。另一组颞侧视网膜的敏感度明显降低，这表明在一些白化病患者中，来自与异常通路相对应的视网膜区域的信息被降解。
