McCormack G L
Invest Ophthalmol. 1975 Dec;14(12):931-5.
The Siamese cat, a type of albino, has a visual pathway anomaly in which too many optic nerve fibers cross at the optic chiasm, and also frequently has strabismus. The correlation of strabismus with this defect suggests that a similar pathway defect without pigmentation anomalies, may be the cause of much human strabismus. Creel, Witkop, and King have used evoked potential methods to show that such a pathway defect likely occurs in the human albino. While unpublished control experiments verified their results on human albinos, no such defect has been found in the normally-pigmented human squinter. It is concluded that the visual pathway anomaly is limited to albinism and is not a likely cause of most human strabismus.
暹罗猫是白化病的一种类型，它存在视觉通路异常，即有过多的视神经纤维在视交叉处交叉，并且还经常患有斜视。斜视与这种缺陷的相关性表明，一种没有色素沉着异常的类似通路缺陷，可能是许多人类斜视的原因。克里尔、维特科普和金使用诱发电位方法表明，这种通路缺陷可能发生在人类白化病患者身上。虽然未发表的对照实验证实了他们对人类白化病患者的研究结果，但在正常色素沉着的斜视患者中未发现这种缺陷。结论是，视觉通路异常仅限于白化病，不太可能是大多数人类斜视的原因。
