Ueda K, Komori Y, Maruo M, Kusaba K
J Cutan Pathol. 1981 Jun;8(3):188-98. doi: 10.1111/j.1600-0560.1981.tb00998.x.
The following features of trichoepithelioma papulosum multiplex (TPM) were revealed by electron microscopy: 1. Proliferation of basaloid cells similar to that in basal cell epithelioma (BCE). 2. Abortive hair shafts and hair papillae. 3. Keratinous cysts surrounded by flat keratinocytes, the cytoplasm of which had small-sized keratohyalin and Odland's bodies. 4. Glycogen deposition near the nuclei, vacuoles filled with amorphous materials and lipid droplets in the cytoplasm of tumor cells. 5. Extracellular compartments, in which fibrous materials, cell fragments, and mucinous substance were found. 6. Melanocytes containing melanosomes in stage II, Langerhans cells involving Birbeck's granules, Merkel cells and other dendritic cells.
多发性丘疹性毛发上皮瘤（TPM）的以下特征通过电子显微镜得以揭示：1. 与基底细胞上皮瘤（BCE）中相似的基底样细胞增殖。2. 发育不全的毛干和毛乳头。3. 由扁平角质形成细胞围绕的角质囊肿，其细胞质含有小尺寸透明角质颗粒和奥德兰小体。4. 肿瘤细胞核附近的糖原沉积、充满无定形物质的空泡以及细胞质中的脂滴。5. 细胞外区域，其中发现有纤维物质、细胞碎片和黏液物质。6. 处于II期含有黑素小体的黑素细胞、涉及伯贝克颗粒的朗格汉斯细胞、默克尔细胞和其他树突状细胞。
