• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Studies of bile acid secretion by isolated rat hepatocytes.

作者信息

Gardner B, Chenouda M S

出版信息

J Lipid Res. 1978 Nov;19(8):985-91.

PMID:731133
Abstract

Bile acid secretion was studied in isolated rat hepatocytes cultured in medium supplemented with cofactors and succinate. Succinate as a respiratory substrate was found to be essential for bile acid synthesis. Feedback mechanism was demonstrated with different inhibitory potency of different bile acids on bile acid synthesis in isolated hepatocytes.

摘要

相似文献

1
Studies of bile acid secretion by isolated rat hepatocytes.
J Lipid Res. 1978 Nov;19(8):985-91.
2
Effect of organic anions on bile acid uptake by isolated rat hepatocytes.有机阴离子对分离的大鼠肝细胞摄取胆汁酸的影响。
Hoppe Seylers Z Physiol Chem. 1978 Aug;359(8):1027-30. doi: 10.1515/bchm.1978.359.1.181.
3
Effect of albumin on bile acid uptake by isolated rat hepatocytes. Is there a common bile acid carrier?白蛋白对分离的大鼠肝细胞摄取胆汁酸的影响。是否存在共同的胆汁酸载体？
Biochem Biophys Res Commun. 1976 Nov 8;73(1):63-71. doi: 10.1016/0006-291x(76)90497-6.
4
Uptake of bile acids by perfused rat liver.灌注大鼠肝脏对胆汁酸的摄取
Am J Physiol. 1976 Sep;231(3):734-42. doi: 10.1152/ajplegacy.1976.231.3.734.
5
Mechanism of ketoconazole-induced elevation of individual serum bile acids in the rat: relationship to the effect of ketoconazole on bile acid uptake by isolated hepatocytes.酮康唑诱导大鼠个体血清胆汁酸升高的机制：与酮康唑对分离肝细胞摄取胆汁酸的影响的关系。
J Pharmacol Exp Ther. 1995 Mar;272(3):1231-7.
6
Cyclosporine-induced interference with uptake of bile acids by human hepatocytes.环孢素对人肝细胞摄取胆汁酸的干扰作用。
Transplant Proc. 1993 Oct;25(5):2892-3.
7
Membrane transport of conjugated and unconjugated bile acids into hepatocytes is susceptible to SH-blocking reagents.结合型和非结合型胆汁酸向肝细胞的膜转运易受巯基阻断剂的影响。
Biochim Biophys Acta. 1990 Nov 2;1029(1):1-12. doi: 10.1016/0005-2736(90)90430-v.
8
Differential feedback regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by rat bile acids in primary monolayer cultures of rat hepatocytes.大鼠肝细胞原代单层培养中大鼠胆汁酸对胆固醇7α-羟化酶mRNA和转录活性的差异反馈调节
Biochem J. 1993 Mar 15;290 ( Pt 3)(Pt 3):685-91. doi: 10.1042/bj2900685.
9
The role of conjugation reactions in enhancing biliary secretion of bile acids.结合反应在增强胆汁酸胆汁分泌中的作用。
Biochem J. 1983 Sep 15;214(3):923-7. doi: 10.1042/bj2140923.
10
Study of cholic acid conjugation by isolated rat hepatocytes.大鼠离体肝细胞胆酸结合作用的研究。
Hoppe Seylers Z Physiol Chem. 1979 Apr;360(4):515-22. doi: 10.1515/bchm2.1979.360.1.515.

引用本文的文献

1
Elevated biliary calmodulin during gallstone formation: the role of bile acids.胆结石形成过程中胆汁钙调蛋白升高：胆汁酸的作用。
Dig Dis Sci. 1998 Jan;43(1):170-7. doi: 10.1023/a:1018852810678.
2
Transport systems of isolated hepatocytes. Studies on the transport of biliary compounds.分离肝细胞的转运系统。胆汁化合物转运的研究。
Arch Toxicol. 1980 Mar;44(1-3):113-26. doi: 10.1007/BF00303188.
3
Effect of spironolactone on p-nitrophenol glucuronidation in isolated rat hepatocytes.
Experientia. 1983 May 15;39(5):527-8. doi: 10.1007/BF01965189.
4
Stimulation of bile acid synthesis by dibutyryl cyclic AMP in isolated rat hepatocytes.二丁酰环磷腺苷对离体大鼠肝细胞胆汁酸合成的刺激作用。
Lipids. 1983 Jul;18(7):443-7. doi: 10.1007/BF02535783.