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脊髓损伤患者的预防性抗凝治疗。

Prophylactic anticoagulant therapy in patients with spinal cord injury.

作者信息

El Masri W S, Silver J R

出版信息

Paraplegia. 1981;19(6):334-42. doi: 10.1038/sc.1981.64.

Abstract

One hundred and two consecutive acute traumatic spinal injury patients admitted between 1976 and 1979 to a male ward at Stoke Mandeville Hospital were considered for prophylactic anticoagulant therapy. Sixty-six were anticoagulated. Thirty-six were not due to various contra-indications. Nineteen patients had pulmonary emboli. None of these were effectively anticoagulated. These results are compared with a similar previous series where there was a smaller incidence of emboli. The main reason for this was due to the delay in admitting patients to the Centre so that they could not be anticoagulated early enough to prevent pulmonary embolus occurring. In these patients who had a pulmonary embolus or were considered to be a high risk, anticoagulant therapy was continued for 6 months.

摘要

1976年至1979年间,连续有102名急性创伤性脊柱损伤患者入住斯托克曼德维尔医院的一个男性病房,他们被考虑接受预防性抗凝治疗。其中66人接受了抗凝治疗。36人因各种禁忌症未接受治疗。19名患者发生了肺栓塞。这些患者中无一接受有效抗凝治疗。将这些结果与之前一个类似系列进行比较,之前系列中栓塞发生率较低。主要原因是患者入住该中心的时间延迟,以至于无法尽早进行抗凝治疗以预防肺栓塞的发生。对于发生肺栓塞或被认为是高危患者,抗凝治疗持续6个月。

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