Dourov N, Cauchie C, de Maertelaere-Laurent E, Meulemans G, Mayer R, Shita F
Nouv Rev Fr Hematol (1978). 1981;23(4):227-34.
In a 56-year-old man with a myeloma marked eosinophilia was discovered. The diagnosis of myeloma was made on the discovery of plasmocyte infiltration in the mandible. Despite surgery and chemotherapy, general bone infiltration by plasma cells occurred over 15 months. The leukocyte count rose to 226,000/mm3 with 162,720 mature eosinophils. Pathogenic problems suggested by such an unusual association (myeloma-eosinophilic leukemoid reaction) are considered.
在一名56岁男性中发现了伴有显著嗜酸性粒细胞增多的骨髓瘤。骨髓瘤的诊断是基于在下颌骨发现浆细胞浸润。尽管进行了手术和化疗,但在15个月内仍出现了浆细胞的全身骨浸润。白细胞计数升至226,000/mm³,其中有162,720个成熟嗜酸性粒细胞。考虑了这种不寻常关联(骨髓瘤-嗜酸性粒细胞白血病样反应)所提示的致病问题。